La ciprofloxacine (Cipro) possède une efficacité démontrée dans les infections urinaires compliquées et les prostatites chroniques, en raison de sa concentration élevée dans les tissus urogénitaux. La molécule inhibe de manière sélective l’ADN-gyrase et la topoisomérase IV, induisant un arrêt de la réplication bactérienne. Sa biodisponibilité est réduite en cas d’administration simultanée avec des produits contenant du magnésium, de l’aluminium ou du fer, ce qui impose un espacement des prises. Les réactions indésirables graves incluent des atteintes tendineuses et des troubles neuropsychiatriques, ayant conduit à des restrictions de prescription dans certains pays européens. Les sources médicales mentionnent aussi que cipro en pharmacie reste indiqué uniquement dans les situations où le bénéfice dépasse le risque documenté.

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